Effect of cimetidine on weight gain in rats.
Indian J Med Sci
;
1995 Nov; 49(11): 257-60
Artigo
em Inglês
| IMSEAR
| ID: sea-67909
ABSTRACT
Effect on food intake and body weight was studied in rats after oral administration of cimetidine. Rats in experimental (E) group exhibited less increase in food intake (20%) compared to control (C) rats (43.8%). Mean body weight showed first reduction (-9.56%) and then very small increment in experimental animals compared to gradual gain in body weight in control animals. At the end of 6 weeks, total gain in body weight was 22.5 gm in rats of E group against 53.8 gm in rats of C group. Food efficiency ratio (FER) showed much reduction (1.13) in E group against 2.07 in C group. These results demonstrate that cimetidine (H2-receptor blocker) may have ability to reduce food intake and body weight in rats.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Ratos
/
Feminino
/
Masculino
/
Aumento de Peso
/
Cimetidina
/
Ratos Wistar
/
Ingestão de Alimentos
/
Antagonistas dos Receptores H2 da Histamina
/
Animais
Idioma:
Inglês
Revista:
Indian J Med Sci
Ano de publicação:
1995
Tipo de documento:
Artigo
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