Life time risk for development of ten major cancers in India and its trends over the years 1982 to 2000.

ABSTRACT

Background: Understanding cancer magnitude, risk and trends will be of help in cancer control programs. Aim: To study trends in cumulative risk up to 64 years of age as lifetime risk of developing major cancers in India during the years 1982 to 2000. Design: Retrospective. Setting: Secondary sources of cancer-registration data. Materials and Methods: Data on age-specific cancer-incidence rates were collected for patients 0-64 years of age of either sex for 10 major cancer sites from the National Cancer Registry Program (NCRP) reports of India from Mumbai, Chennai, Bangalore, Bhopal and Delhi; and Barshi registries for the years 1982 or 1988 to 2000. Statistical Analysis: Cumulative risks computed for lifetime development of cancer. Linear trends were studied using simple linear regressions. Results: The lifetime risk among females for the10 cancer sites ranged from 0.02 to 3.3% and from 0.04 to 2.4% for the years 1982 and 2000 respectively; whereas among males, it ranged from 0.04 to 0.89% and from 0.05 to 0.95% respectively. Significant (P P P P Conclusion: Significant and higher rates of positive trends in lifetime cancer risks for breast cancer among females and for NHL among both sexes were observed.