Anti-nuclear antibody positivity in multi-transfused thalassemia major.
Indian Pediatr
;
1992 May; 29(5): 607-10
Artigo
em Inglês
| IMSEAR
| ID: sea-7039
ABSTRACT
The frequency of anti-nuclear antibodies (ANA) was evaluated in multi-transfused patients of thalassemia major. Twelve out of 83 patients (14.5%) had positive ANA at titres of 180 or above. The results were compared with age and sex matched healthy controls who showed positive results in only 1 of 52 cases (1.9%; p less than 0.05). Antibody against double stranded DNA was absent. ANA positivity was found to correlate with higher age (p less than 0.01), more amount of blood transfused (p less than 0.01), splenectomy status (p less than 0.01), higher levels of serum ferritin (p less than 0.01) and presence of hepatitis B surface antigen (p less than 0.01) and antihepatitis C antibody (p less than 0.01).
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Talassemia
/
Transfusão de Sangue
/
Feminino
/
Humanos
/
Masculino
/
Criança
/
Pré-Escolar
/
Anticorpos Antinucleares
/
Adolescente
/
Adulto
Idioma:
Inglês
Revista:
Indian Pediatr
Ano de publicação:
1992
Tipo de documento:
Artigo
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