Familial unilateral Brown syndrome.
Indian J Ophthalmol
;
2008 Sep-Oct; 56(5): 430-4
Artigo
em Inglês
| IMSEAR
| ID: sea-70796
ABSTRACT
We present a two-generation family with Brown syndrome. The proband was a six and a half-year-old female who presented with a history of failure of dextro-elevation of her left eye. A full ophthalmic evaluation was consistent with a left Brown syndrome. Family history revealed that her mother was operated on as a child for left Brown syndrome and examination of her four and a half-year-old sibling showed similar affection in the left eye. Autosomal dominant inheritance has been postulated in this condition. To our knowledge this is the first report of three members of a two-generation family with left-sided Brown syndrome. Genetic counseling of Brown syndrome cases is advised; nevertheless, identification of the responsible gene should shed more light on its genetics.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Linhagem
/
Fenótipo
/
Feminino
/
Humanos
/
Masculino
/
Visão Binocular
/
Núcleo Familiar
/
Transtornos da Motilidade Ocular
/
Criança
/
Seguimentos
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Idioma:
Inglês
Revista:
Indian J Ophthalmol
Ano de publicação:
2008
Tipo de documento:
Artigo
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