Topical sulindac therapy in diabetic senile cataracts: cataract-IV.
Indian J Ophthalmol
;
1989 Jul-Sep; 37(3): 127-33
Artigo
em Inglês
| IMSEAR
| ID: sea-71044
ABSTRACT
Sulindac, a non-steroidal anti-inflammatory drug has been found to be a potent inhibitor of enzyme aldose reductase. We used sulindac topically in diabetic senile cataract patients to note if it effects the progression of cataracts. More of sulindac treated eyes maintained initial vision and fewer eyes had visual loss of up to two lines or more as compared to control eyes. The extent and density of different opacities showed less progression in sulindac treated eyes but it was not statistically significant except that the ophthalmoscopically observed density of opacity showed statistically very significant lesser mean increase in sulindac treated eyes. We suggest that sulindac is a potential drug which should be further evaluated in large double blind photodocumented studies in diabetic senile cataracts.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Catarata
/
Idoso
/
Feminino
/
Humanos
/
Masculino
/
Envelhecimento
/
Sulindaco
/
Seguimentos
/
Administração Tópica
/
Complicações do Diabetes
Tipo de estudo:
Ensaio Clínico Controlado
/
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Idioma:
Inglês
Revista:
Indian J Ophthalmol
Ano de publicação:
1989
Tipo de documento:
Artigo
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