Serological responses to hepatitis B virus infection in multi-transfused thalassemic children.
Indian Pediatr
;
1992 Jan; 29(1): 73-7
Artigo
em Inglês
| IMSEAR
| ID: sea-7150
ABSTRACT
One hundred children with beta-thalassemia major were studied prospectively. A one time analysis of serum samples was carried out for a battery of hepatitis B viral markers viz., HBsAg, anti-HBs and anti-HBc. Seven mutually different serological patterns were observed. The commonest profile seen in 49 patients was a combined seropositivity for anti-HBc and anti-HBs indicating past HBV infection with persisting immunity. Definite evidence of active HBV infection (seropositivity for HBsAg and/or HBeAg) was demonstrated in 10 cases, six of these were HBsAg positive. Anti-HBc positivity alone was detected in 17 patients. The remaining 24 children were seropositive for anti-HBs alone suggesting a possible passive transmission of anti-HBs through blood transfusion.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Talassemia
/
Transfusão de Sangue
/
Humanos
/
Criança
/
Pré-Escolar
/
Países em Desenvolvimento
/
Hepatite B
/
Anticorpos Anti-Hepatite B
/
Antígenos de Superfície da Hepatite B
/
Índia
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Indian Pediatr
Ano de publicação:
1992
Tipo de documento:
Artigo
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