Selenite cataract and its attenuation by vitamin E in Wistar rats.
Indian J Ophthalmol
;
2003 Jun; 51(2): 161-70
Artigo
em Inglês
| IMSEAR
| ID: sea-72173
ABSTRACT
PURPOSE:
To study the role of vitamin E in preventing cataract formation in experimental animals.METHODS:
An experimental model (selenite cataract) was selected for this study. Selenite cataract was produced in rats by subcutaneous administration of sodium selenite. Biochemical and histological changes following induction of selenite cataract in weanling Wistar rats were studied vis-a-vis the role of vitamin E in attenuating or preventing cataractogenesis.RESULTS:
Vitamin E was capable of preventing selenite cataractogenesis. Selenite cataract did not develop in 91.6% (11 of 12) and 76.7% (8 of 12) vitamin E treated rats, when administered on the 12th and 10th post partum day respectively.CONCLUSION:
The study confirmed that selenite induced cataract in Wistar rats is attenuated by vitamin E.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Ratos
/
Vitamina E
/
Catarata
/
Ratos Wistar
/
Selenito de Sódio
/
Cristalinas
/
Eletroforese em Gel de Poliacrilamida
/
Cristalino
/
Animais
/
Animais Recém-Nascidos
Idioma:
Inglês
Revista:
Indian J Ophthalmol
Ano de publicação:
2003
Tipo de documento:
Artigo
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