Clinical spectrum of HIV infection.
Indian Pediatr
;
2000 Aug; 37(8): 831-6
Artigo
em Inglês
| IMSEAR
| ID: sea-7314
ABSTRACT
OBJECTIVE:
To study the modes of transmission of pediatric HIV infection, to categorize clinical manifestations and to compare clinical spectrum of perinatal with transfusion acquired HIV infection.DESIGN:
Case series study.SETTING:
Hospital based pediatric HIV clinic.METHODS:
Children confirmed to have HIV infection were evaluated and relevant details recorded.RESULTS:
55 children were enrolled of whom 41 (74.5%) had perinatal transmission of HIV, 12 (21.8%) were infected through blood transfusions and 2 (3.6%) through other routes. Thirty-seven (90.2%) of the 41 perinatally infected children were symptomatic. Tuberculosis was seen in 25 (67.5%) of these children and failure to thrive in 18 (48.6%). Nonspecific features such as recurrent bacterial infection, oral candidiasis and chronic diarrhea were other manifestations. Eight (26.3%) of the 30 children available for follow up for a median period of 9 months died at the median age of 8.5 months. Amongst the transfusion acquired HIV infection, 11 (91.6%) of the 12 were asymptomatic at presentation. Six (50%) of these children died at the median age of 3 years and the remaining 6 had no major symptoms at a median follow up of 3.5 years.CONCLUSION:
Perinatal route is the major route of HIV transmission in children and clinical manifestations are different from those of adults.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Complicações Infecciosas na Gravidez
/
Feminino
/
Humanos
/
Masculino
/
Gravidez
/
Infecções por HIV
/
Criança
/
Pré-Escolar
/
Adolescente
/
Transmissão Vertical de Doenças Infecciosas
Idioma:
Inglês
Revista:
Indian Pediatr
Ano de publicação:
2000
Tipo de documento:
Artigo
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