Immune status of children suffering from minimal change nephrotic syndrome.
Indian J Pathol Microbiol
;
1992 Jul; 35(3): 171-9
Artigo
em Inglês
| IMSEAR
| ID: sea-73310
ABSTRACT
Twenty five children suffering from minimal change nephrotic syndrome were studied for immunological alterations at different stages of this disease i.e., onset, relapse and remission. Changes were found mainly at onset and during relapse in the form of altered helper and suppressor cell ratio, depressed delayed cutaneous hypersensitivity reaction, decreased S-IgG bearing lymphocytes with low serum IgG concentration, and increased S-IgM bearing lymphocytes with high serum IgM concentration. Majority of these parameters returned to normal values during remission. Serum IgE was found high at all stages of this. These alterations suggest defects in cell mediated immunity resulting in secretion of some substance which modifies the glomerular anionic charges.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Recidiva
/
Feminino
/
Humanos
/
Masculino
/
Criança
/
Pré-Escolar
/
Corticosteroides
/
Imunidade Celular
/
Lactente
/
Formação de Anticorpos
Idioma:
Inglês
Revista:
Indian J Pathol Microbiol
Ano de publicação:
1992
Tipo de documento:
Artigo
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