Spindle cell neoplasm of skin: diagnostic dilemma.
Indian J Pathol Microbiol
;
2007 Oct; 50(4): 814-6
Artigo
em Inglês
| IMSEAR
| ID: sea-73349
ABSTRACT
Poorly differentiated, spindle cell malignancies, on sun damaged skin frequently pose a diagnostic challenge for pathologists. The vast majority of these neoplasms ultimately are diagnosed as either atypical fibroxanthoma (AFX), spindle cell melanoma (SCM), and very rarely as spindle cell squamous cell carcinoma (SCSCC), leiomyosarcoma or angiosarcoma. Light microscopic clues may suggest one of these neoplasms, but subtle and overlapping characteristics often render precise diagnosis impossible based on morphological features alone. Immunohistochemistry therefore is necessary to firmly and accurately diagnose the majority of spindle cell malignancies on sun damaged skin. Aim of this case report is to highlight the practical approach to such diagnostic dilemmas.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Sarcoma
/
Neoplasias Cutâneas
/
Vimentina
/
Idoso de 80 Anos ou mais
/
Feminino
/
Humanos
/
Imuno-Histoquímica
/
Carcinoma de Células Escamosas
/
Proteínas S100
/
Xantomatose
Tipo de estudo:
Estudo diagnóstico
Limite:
Aged80
Idioma:
Inglês
Revista:
Indian J Pathol Microbiol
Ano de publicação:
2007
Tipo de documento:
Artigo
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