Tumor marker studies of cervical smears: an immunohistochemical approach.
Indian J Pathol Microbiol
;
1994 Jan; 37(1): 45-51
Artigo
em Inglês
| IMSEAR
| ID: sea-73462
ABSTRACT
Immunoreactivity with monoclonal antibodies against epithelial membrane antigen (EMA), vimentin, squamous epithelium-specific keratin, nonsquamous epithelium-specific keratin, and polyclonal antibodies epithelial cells of 55 cervical smears using the avidin-biotin-peroxidase complex and indirect immunoperoxidase methods to detect antigens. Most of the abnormal squamous cells with few normal cells were reactive for EMA but the intensity of the reaction was variable in both cases. There was no correlation in the reactivity between normal and abnormal cells with different cytokeratins varying in their molecular weight. Vimentin was also reactive with both cells. The results of this experiment suggest that antibodies used, appear to be of limited usefulness in the diagnosis of cervical smears.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Esfregaço Vaginal
/
Vimentina
/
Feminino
/
Humanos
/
Glicoproteínas de Membrana
/
Biomarcadores Tumorais
/
Neoplasias do Colo do Útero
/
Técnicas Imunoenzimáticas
/
Sensibilidade e Especificidade
/
Mucina-1
Tipo de estudo:
Estudo diagnóstico
Idioma:
Inglês
Revista:
Indian J Pathol Microbiol
Ano de publicação:
1994
Tipo de documento:
Artigo
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