Study of haemoglobin S percentage and haematological parameters in sickle cell trait.
Indian J Pathol Microbiol
;
2003 Jul; 46(3): 420-4
Artigo
em Inglês
| IMSEAR
| ID: sea-73888
ABSTRACT
A total of 101 individuals who showed AS pattern on haemoglobin electrophoresis were included in this study and various haematological investigations were carried out on them. Of these, 79 cases were grouped as AS patients. Twenty two healthy relatives of sickle anemia patients were grouped as AS controls. Twenty AA controls were also included in this study. Haemoglobin S (HbS) and hemoglobin A (HbA) quantitation was carried out. The frequency distribution of HbS percentage showed that maximum subjects had HbS levels above 33%. A female predominance was seen in subjects of sickle cell trait. Haemoglobin levels and total red cell counts of AS patients were found to be significantly lower than those of AS controls. Reticulocyte counts and hematocrit values of AS patients were found to be significantly higher than AS controls. MCV and MCH values of AS patients were found to be significantly lower, but MCHC was not significantly altered.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Traço Falciforme
/
Feminino
/
Humanos
/
Masculino
/
Hemoglobina A
/
Hemoglobina Falciforme
/
Estudos de Casos e Controles
/
Adulto
/
Contagem de Eritrócitos
/
Índices de Eritrócitos
Tipo de estudo:
Estudo observacional
Idioma:
Inglês
Revista:
Indian J Pathol Microbiol
Ano de publicação:
2003
Tipo de documento:
Artigo
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