Nerve cell markers in ossifying fibromyxoid tumour of soft parts.
Indian J Pathol Microbiol
;
2001 Apr; 44(2): 163-7
Artigo
em Inglês
| IMSEAR
| ID: sea-74265
ABSTRACT
Reported herein are two benign ossifying fibromyxoid tumors (OFMTs) of the soft tissues in axilla and terminal phalanx respectively. Both cases on immunohistochemistry (IHC) showed reactivity for vimentin, S-100 protein and glial fibrillary acidic protein (GFAP) antibodies. In addition, a focal/diffuse strong positivity for neurofilament (NF) and neuron specific enolase (NSE) was observed. Electron microscopy in one instance revealed abundant intermediate filaments, primitive cell junctions and a focally present external lamina. In the light of nerve cell differentiation of these tumors and the similarity of IHC profile and EM features of OFMT to a poorly differentiated malignant peripheral nerve sheath tumor (MPNST); it is suggested that OFMT is a variably differentiated PNST rather than a simple Schwannian neoplasm as is believed.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Fosfopiruvato Hidratase
/
Neoplasias de Tecidos Moles
/
Vimentina
/
Humanos
/
Masculino
/
Proteínas S100
/
Biomarcadores Tumorais
/
Ossificação Heterotópica
/
Neoplasias de Bainha Neural
/
Adulto
Idioma:
Inglês
Revista:
Indian J Pathol Microbiol
Ano de publicação:
2001
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS