Direct immunofluorescent studies of skin biopsies in pemphigus.
Indian J Pathol Microbiol
;
1994 Jan; 37(1): 59-63
Artigo
em Inglês
| IMSEAR
| ID: sea-74605
ABSTRACT
Direct immunofluorescent studies of skin biopsies from 16 pemphigus vulgaris patients revealed immunoglobulin deposits in 12 (75%) cases with fluorescence at intercellular areas in epidermis. In 2 patients (12.5%) dermoepidermal junction also showed immunoglobulin deposits. IgG was the commonest type of immunoglobulin demonstrated in 12 out of 16 (75%) cases followed by IgM in 5 (31.25%) and IgA in 1 (6.25%) cases. Seven (43.75%) cases showed presence of IgG alone while IgM with IgG was found in 4 (25%) cases. One (6.25%) case showed deposition of IgG, IgM and IgA. The results indicated that demonstration of immunoglobulin in skin biopsies by direct immunofluorescent technique is quite a useful adjunct in diagnostic confirmation of pemphigus.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Pele
/
Isotipos de Imunoglobulinas
/
Feminino
/
Humanos
/
Masculino
/
Imunofluorescência
/
Pênfigo
/
Adulto
Idioma:
Inglês
Revista:
Indian J Pathol Microbiol
Ano de publicação:
1994
Tipo de documento:
Artigo
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