Alpha-fetoprotein in germ cell tumors. An immunohistochemical study.
Indian J Pathol Microbiol
;
1989 Jul; 32(3): 167-73
Artigo
em Inglês
| IMSEAR
| ID: sea-74797
ABSTRACT
Total 40 cases of testicular and ovarian germ cell tumors and one case of extragonadal germ cell tumor were studied for the presence of alphafetoprotein (AFP) by indirect immunoperoxidase technique. All seminomas (7 cases) and teratomas (13 cases) were negative for AFP; while 85% of the pure embryonal carcinomas, (E.C.) all pure yolk sac tumors (Y.S.T.) (7 cases) and all embryonal carcinoma and yolk sac components in mixed tumors were AFP positive. Immunostaining of tumor marker appeared to help only in differentiating seminomatous and nonseminomatous tumors and hence does not provide any additional information for classification of these tumors.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Neoplasias Ovarianas
/
Neoplasias Testiculares
/
Feminino
/
Humanos
/
Masculino
/
Imuno-Histoquímica
/
Alfa-Fetoproteínas
/
Neoplasias Embrionárias de Células Germinativas
Idioma:
Inglês
Revista:
Indian J Pathol Microbiol
Ano de publicação:
1989
Tipo de documento:
Artigo
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