Embryonal rhabdomyosarcoma of the chest wall: a case report and review of the literature.
Indian J Pathol Microbiol
;
2008 Apr-Jun; 51(2): 274-6
Artigo
em Inglês
| IMSEAR
| ID: sea-74855
ABSTRACT
Embryonal rhabdomyosarcoma is a soft-tissue sarcoma which has a predilection for the head and neck area, genitourinary tract and the extremities. We report a rare case of embryonal rhabdomyosarcoma of the chest wall in an 8-year-old girl, presenting as a destructive tumor in the rib and clinically and radiologically mimicking Ewing's sarcoma. Histopathological examination showed a small round cell tumor. Immunohistochemically, the positivity for muscle markers desmin and myogenin in the tumor cells proved to be useful for making a definitive diagnosis of embryonal rhabdomyosarcoma. Cytogenetic analysis revealed a high level of aneuploidy in the tumor cells, with double-minutes and additional chromosomal structural aberrations. The patient is responding well to chemotherapy.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Sarcoma de Ewing
/
Neoplasias Torácicas
/
Feminino
/
Humanos
/
Criança
/
Rabdomiossarcoma Embrionário
/
Parede Torácica
/
Diagnóstico Diferencial
/
Aneuploidia
Tipo de estudo:
Estudo diagnóstico
Idioma:
Inglês
Revista:
Indian J Pathol Microbiol
Ano de publicação:
2008
Tipo de documento:
Artigo
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