Comparison of endoscopic brush cytology with biopsy for detection of Helicobacter pylori in patients with gastroduodenal diseases.
Indian J Pathol Microbiol
;
2001 Jul; 44(3): 283-8
Artigo
em Inglês
| IMSEAR
| ID: sea-74867
ABSTRACT
Upper GI endoscopy was performed in 50 adult patients attending the gastroenterology OPD with gastroduodenal diseases. Gastric antral mucosal brushings were taken for cytological evaluation and urea broth test followed by antral biopsy. The slides prepared were stained with Wright Giemsa (WG), Hema toxylin & Eosin (H&E) and Papanicolaou (Pap). Brush Cytology Smears were compared with biopsy sections for detection of Helicobacter pylori and the staining techniques were evaluated to see which stain was easiest to perform and interpret on routine basis. H&E stained sections were examined for histomorphological parameters associated with H. pylori infection. Brush cytology was rapid and simple with observed sensitivity of 90% and specificity of 100%. On evaluating the various stains, M.B. and W.G. were found to the rapid and easy to perform and the bacteria stood out very well against the background. Of the histomorphological parameters studied, presence of actively and lymphoid aggregates and absence of intestinal metaplasia correlated positively with the presence of the bacteria. Cytological brushing urea broth test was not very sensitive (55.2%) and specific (51%) for detection of the bacteria.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Coloração e Rotulagem
/
Biópsia
/
Idoso
/
Humanos
/
Helicobacter pylori
/
Infecções por Helicobacter
/
Técnicas Bacteriológicas
/
Sensibilidade e Especificidade
/
Adulto
/
Citodiagnóstico
Tipo de estudo:
Estudo diagnóstico
Idioma:
Inglês
Revista:
Indian J Pathol Microbiol
Ano de publicação:
2001
Tipo de documento:
Artigo
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