Acute basophilic leukaemia: a case report.
Indian J Pathol Microbiol
;
2007 Apr; 50(2): 443-6
Artigo
em Inglês
| IMSEAR
| ID: sea-74978
ABSTRACT
Acute basophilic leukaemia is an uncommon form of acute leukaemia, rarely occurring as de novo disease. Due to rarity of the disease, consistent diagnostic criteria for the identification of this entity still remain the topic of discussion. Immunophenotypic profile, electron microscopy and cytogenetic analysis in addition to morphological features, are said to be highly desirable for correct identification of this entity. In set-up like ours, where such facilities are either not available or not in reach of the patients due to financial constraints, morphological features and simple technique like demonstration of metachromasia in blasts with toluidine blue stain remain the most useful diagnostic tool for identification of this rare condition. We present a case of acute basophilic leukaemia with (11q23)-MLL gene rearrangement, in an 18-year-old male with review of literature and discussion of diagnostic criteria.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Coloração e Rotulagem
/
Cloreto de Tolônio
/
Humanos
/
Masculino
/
Rearranjo Gênico
/
Leucemia Basofílica Aguda
/
Adolescente
/
Corantes
/
Proteína de Leucina Linfoide-Mieloide
Tipo de estudo:
Estudo prognóstico
Idioma:
Inglês
Revista:
Indian J Pathol Microbiol
Ano de publicação:
2007
Tipo de documento:
Artigo
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