AgNOR counts are not altered in alcoholic cirrhosis.
Indian J Pathol Microbiol
;
2003 Apr; 46(2): 170-2
Artigo
em Inglês
| IMSEAR
| ID: sea-75409
ABSTRACT
One hundred and two liver biopsy specimens were stained for Argyrophilic nucleolar organizer regions and associated proteins to assess its utility in differentiating normal, cirrhotic and neoplastic liver tissue. A statistically significant (p < 0.001) difference was observed between mean AgNOR counts of normal (1.53 +/- 0.4), post-hepatitic cirrhosis (3.65 +/- 0.53) and hepatocellular carcinoma (7.94 +/- 1.18). In contrast the mean AgNOR count of biopsies with alcoholic cirrhosis (1.57 +/- 0.06) was significantly less (p < 0.001) than post-hepatitic cirrhosis and was similar to that of normal liver tissue. It is concluded that AgNORs can act as a good adjuvant to histology in diagnosing liver diseases especially in differentiating post-hepatitic and alcoholic cirrhosis.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Prata
/
Coloração e Rotulagem
/
Humanos
/
Estudos de Casos e Controles
/
Carcinoma Hepatocelular
/
Hepatite
/
Fígado
/
Cirrose Hepática
/
Cirrose Hepática Alcoólica
/
Neoplasias Hepáticas
Tipo de estudo:
Estudo observacional
/
Fatores de risco
Idioma:
Inglês
Revista:
Indian J Pathol Microbiol
Ano de publicação:
2003
Tipo de documento:
Artigo
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