Inhibition of HBsAg secretion from Alexander cell line by Phyllanthus amarus.
Indian J Pathol Microbiol
;
1996 Jul; 39(3): 211-5
Artigo
em Inglês
| IMSEAR
| ID: sea-75614
ABSTRACT
Alexander cell line, an human hepatocellular carcinoma derived cell line which has the property of secreting HBsAg in the supernatant was used to study the antiviral property of phyllanthus amarus. Aquous extract of Phyllanthus amarus was evaluated for its in vitro ability to inhibit HBsAg secretion on a dose dependent manner. It was seen that P. amarus at 1mg/ml concentration on a single dose inhibited the secretion of HBsAg for a period of 48 hours. This experiment proved the anti hepatitis B virus property of P. amarus at cellular level and further confirmed its beneficial use in the treatment of acute and chronic hepatitis B and healthy carriers of HBV.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Antivirais
/
Plantas Medicinais
/
Humanos
/
Células Tumorais Cultivadas
/
Extratos Vegetais
/
Carcinoma Hepatocelular
/
Antígenos de Superfície da Hepatite B
/
Neoplasias Hepáticas
/
Antineoplásicos Fitogênicos
Idioma:
Inglês
Revista:
Indian J Pathol Microbiol
Ano de publicação:
1996
Tipo de documento:
Artigo
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