Detection of HPV16 and 18 by in situ hybridization in precancerous and cancerous lesions of cervix.
Indian J Pathol Microbiol
;
2006 Jul; 49(3): 345-7
Artigo
em Inglês
| IMSEAR
| ID: sea-75658
ABSTRACT
Fifty cervical biopsies from women with preinvasive and invasive malignancies of uterine cervix and ten normal cervical biopsies were examined for the presence of human papilloma virus (HPV) 16 and 18 DNA sequences by in situ hybridization (ISH) method with biotinylated DNA probes. The overall positivity of HPV DNA was 48% (24/50). The positivity of HPV 16 DNA for low grade squamous intraepithelial lesion (LSIL), high grade squamous intraepithelial lesions (HSIL) and squamous cell carcinoma (SCC) were 33.33%, 45.45%, 42.30% respectively. The positivity for HPV 18 DNA for LSIL, HSIL and SCC were 0%, 18.18%, 30.76% respectively. Two cases of cervical adenocarcinomas showed positivity for HPV 18 DNA only.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Biópsia
/
Feminino
/
Humanos
/
DNA Viral
/
Carcinoma de Células Escamosas
/
Sondas de DNA
/
Neoplasias do Colo do Útero
/
Colo do Útero
/
Hibridização In Situ
/
Biotinilação
Tipo de estudo:
Estudo diagnóstico
Idioma:
Inglês
Revista:
Indian J Pathol Microbiol
Ano de publicação:
2006
Tipo de documento:
Artigo
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