The histopathology of chronic gastritis.
Indian J Pathol Microbiol
;
2007 Jan; 50(1): 18-24
Artigo
em Inglês
| IMSEAR
| ID: sea-75722
ABSTRACT
Chronic gastritis is a multifactorial disorder thought to be influenced by bacterial and host genetic factors. Histopathological examination is the mainstay of diagnosis, however features like the presence of Helicobacter pylori are difficult to evaluate on biopsy. We evaluated 120 gastric antral biopsies using the revised Sydney system. The density of the inflammatory infiltrate, H pylori and mast cells were evaluated. It was seen that the presence of H pylori is strongly associated with an acute and a chronic inflammatory infiltrate. The presence of neutrophils on biopsy is strongly associated with the presence of H pylori and with the density and the grade of the chronic inflammatory infiltrate. The chronic inflammatory response is an intermediary between the acute inflammatory process and glandular atrophy. The lymphocytic infiltrate is also a precursor lesion of the lymphoid follicles. The presence of mast cells does not appear to be related to any of the other inflammatory parameters. The presence of one feature is a strong indicator for the presence of other inflammatory features.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Antro Pilórico
/
Atrofia
/
Biópsia
/
Humanos
/
Linfócitos
/
Doença Crônica
/
Helicobacter pylori
/
Gastrite
/
Histocitoquímica
/
Inflamação
Idioma:
Inglês
Revista:
Indian J Pathol Microbiol
Ano de publicação:
2007
Tipo de documento:
Artigo
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