Hematological responses to hydroxyurea therapy in multitransfused thalassemic children.
Indian J Pediatr
;
1997 May-Jun; 64(3): 395-8
Artigo
em Inglês
| IMSEAR
| ID: sea-80018
ABSTRACT
Fifteen multi-transfused thalassemic children between 3-6 years of age (seven boys and eight girls) were administered hydroxyurea for 5 days and three such cycles were repeated at 15 days interval. Rise in hemoglobin levels was observed in 13, 8 and 7 cases, while rise in mean hemoglobin F was seen in 8, 11 and 10 cases following 1st, 2nd and 3rd course of hydroxyurea therapy respectively. Rise in hemoglobin level was associated with transient rise in fetal hemoglobin level. Though the changes in mean hemoglobin levels and hemoglobin F levels were statistically insignificant, a definite trend of rise in hemoglobin and hemoglobin F was observed.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Transfusão de Sangue
/
Feminino
/
Humanos
/
Masculino
/
Hemoglobina Fetal
/
Esquema de Medicação
/
Criança
/
Pré-Escolar
/
Seguimentos
/
Resultado do Tratamento
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Idioma:
Inglês
Revista:
Indian J Pediatr
Ano de publicação:
1997
Tipo de documento:
Artigo
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