Advances in management of sickle cell disease.
Indian J Pediatr
;
2003 Aug; 70(8): 649-54
Artigo
em Inglês
| IMSEAR
| ID: sea-80402
ABSTRACT
Sickle cell disease is numerically as common as thalassaemia. However, it affects relatively under privileged population i.e. tribal population belonging to economically poor class and having inadequate access to education and modern health facilities. A recent explosion acknowledged in understanding the pathogenesis of this disease has lead to newer dimensions in treatment. Some of these viz. prevention of overwhelming bacterial infection, present indications and controversies regarding blood transfusion, prevention of stroke, acute chest syndrome, hydroxyurea therapy--probably the best disease modifying agent at the moment, stem cell transplantation--a cure and certain promising experimental therapies including gene therapy have been discussed in this review.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Doenças Respiratórias
/
Síndrome
/
Infecções Bacterianas
/
Transfusão de Sangue
/
Humanos
/
Recém-Nascido
/
Criança
/
Pré-Escolar
/
Doença Aguda
/
Adolescente
Idioma:
Inglês
Revista:
Indian J Pediatr
Ano de publicação:
2003
Tipo de documento:
Artigo
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