Adverse events associated with neonatal exchange transfusion for hyperbilirubinemia.

ABSTRACT

OBJECTIVE: The main purpose of hyperbillirubin treatment is to prevent high billirubin concentration that may cause Kernicterus. We conducted this study to estimate the incidence of blood exchange and determine causes and complication of blood exchange and identify strategies for risk reduction of Kernicterus in newborn with jaundice. METHODS: From march 2004 to march 2006 in neonatal Department in children hospital, medical center Tehran, Iran, 346 neonates were admitted as neinatal jaundice without sign and symptoms of infections. We identified causes and complications of exchange. data processing and analysis was conducted by SPSS versions 11.5. RESULTS: Of 346 infants with jaundice who received phototherapy. 50, 14.45 percent cases underwent exchange transfusion with mean age 9.38+5.75 days. The mean total Serum billirubin level was 29.39+6.13mg/dl. ABO incompatibility was the most common cause for hyperbillirubinemia.the incidence of apnea was 12% there was no direct death frmo exchange transfusion. CONCLUSION: To make payment women aware to cbserve jaundice regularly after birth of their child and short breast feeding to control dehydretion.