Detection of high risk pregnancies with relation to ABO haemolytic disease of newborn.

ABSTRACT

IgM and IgG anti A and anti B antibody status of 100 antenatal O group mothers (who had non O group husbands) were studied. Of these, 3 mothers had an IgM anti A antibody levels ranging from 1512 to 12048 and IgG ranging from 11204 to 12048, IgM anti B ranging from 1128 to 1512 and IgG anti B ranging from 1256 to 1512. All these mothers had A + ve children and all these children suffered from ABO haemolytic disease of newborn (HDN). A 4th mother had an IgM anti A titre of 164 and IgG anti A titre of 116. The titre of IgM anti B in this mother was 1512 and that of IgG 11024. The child was A + ve and did not suffer from ABO haemolytic disease of newborn.