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The adverse effect of marginally higher lead level on intelligence development of children: a Shanghai study.
Indian J Pediatr ; 1992 Mar-Apr; 59(2): 233-8
Artigo em Inglês | IMSEAR | ID: sea-83133
ABSTRACT
We surveyed 128 preschool children in a lead-polluted area in Shanghai to study the relationship between blood lead level and neuropsychological functions, assessed by age-appropriate psychological tests. The geometric means of blood lead level was 21.7 + -10.8 micrograms/dl. Of 47 children aged below 30 months, there was no significant difference in BSID indices between the high and low lead subjects, although the high lead children tended to have poorer development scores than the low lead ones. On the other hand, of 81 children older than 46 months, the WPPSI IQ scores showed highly significant negative correlation with blood lead level. Step-wise regression and multiple analysis of covariance techniques were employed to find out and control the confounding factors. Even when 21 non-lead variables were considered, the IQ difference between high and low lead groups remained statistically significant. We concluded that the children, especially those older than 46 months, in the area investigated, did suffer from lead toxicity causing impairment in intelligence development. We support the view that marginally higher lead level in children should be taken seriously.
Assuntos
Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Assunto principal: Comportamento Verbal / Escalas de Wechsler / Feminino / Humanos / Masculino / Criança / Deficiências do Desenvolvimento / Pré-Escolar / China / Análise Multivariada País/Região como assunto: Ásia Idioma: Inglês Revista: Indian J Pediatr Ano de publicação: 1992 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Assunto principal: Comportamento Verbal / Escalas de Wechsler / Feminino / Humanos / Masculino / Criança / Deficiências do Desenvolvimento / Pré-Escolar / China / Análise Multivariada País/Região como assunto: Ásia Idioma: Inglês Revista: Indian J Pediatr Ano de publicação: 1992 Tipo de documento: Artigo