Sodium valproate -- induced skeletal myopathy.
Indian J Pediatr
;
2005 Mar; 72(3): 243-4
Artigo
em Inglês
| IMSEAR
| ID: sea-83151
ABSTRACT
The authors report a case of skeletal myopathy in a four-year-old boy on long-term sodium valproate therapy for secondary epilepsy due to neurocysticercosis. He presented with clinical features of limb girdle weakness. EMG revealed features of myopathy. Carnitine deficiency due to sodium valproate was suspected and plasma carnitine levels were found to be low. Sodium valproate was withdrawn. L-carnitine supplementation resulted in marked clinical recovery as well as rise in plasma carnitine levels.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Deficiência de Vitaminas do Complexo B
/
Humanos
/
Masculino
/
Carbamazepina
/
Carnitina
/
Pré-Escolar
/
Ácido Valproico
/
Epilepsia
/
Doenças Musculares
/
Anticonvulsivantes
Idioma:
Inglês
Revista:
Indian J Pediatr
Ano de publicação:
2005
Tipo de documento:
Artigo
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