Detection of tubercule antigen in cerebrospinal fluids by ELISA for diagnosis of tuberculous meningitis.
Indian J Pediatr
;
1990 Sep-Oct; 57(5): 679-83
Artigo
em Inglês
| IMSEAR
| ID: sea-83440
ABSTRACT
An Enzyme Linked Immunosorbent Assay (ELISA) was standardised to detect the presence of tubercule antigen in cerebrospinal fluids from patients with meningitis. CSF samples from clinically suspected cases of tuberculous meningitis, culture proven pyogenic meningitis and non-bacterial aseptic central nervous system (CNS) disorders were tested by ELISA to demonstrate its potential utility for routine diagnostic purpose. Tubercule antigen was detected in 73% cases of tuberculous meningitis and was absent in pyogenic and other non-bacterial CNS disorder cases. The test appears to be a promising approach for a definitive diagnosis of tuberculous meningitis.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Humanos
/
Ensaio de Imunoadsorção Enzimática
/
Seguimentos
/
Diagnóstico Diferencial
/
Mycobacterium tuberculosis
/
Antígenos de Bactérias
Tipo de estudo:
Estudo diagnóstico
/
Estudo observacional
/
Estudo prognóstico
Idioma:
Inglês
Revista:
Indian J Pediatr
Ano de publicação:
1990
Tipo de documento:
Artigo
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