Bone marrow trephine biopsy as an adjunct to bone marrow aspiration.
Artigo
em Inglês
| IMSEAR
| ID: sea-85182
ABSTRACT
OBJECTIVE:
To determine the relative efficacy of bone marrow aspiration as compared to that of trephine biopsy.METHODS:
Bone marrow aspiration and bilateral trephine biopsies were performed in 420 consecutive cases. The diagnosis and findings made on bone marrow aspiration were compared with that made on trephine biopsy in each case.RESULTS:
Aspiration alone was sufficient in making a diagnosis in 372 (88.6%) cases as it correlated well with the diagnosis made on trephine sections. In the remaining 48 (11.4%) cases trephine biopsy was necessary for making a diagnosis due to incomplete information provided by aspiration or its inability to give a correct diagnosis. These cases were mostly hypoplastic/aplastic marrow, myelofibrosis and marrow involvement by metastatic tumour and lymphomatous infiltration. Often a bilateral marrow biopsy picked up the diagnostic lesion.CONCLUSION:
The decision to perform a marrow aspiration alone or in combination with marrow biopsy depends on the diagnosis being considered. In nutritional anaemias, most hematologic malignancies and immune thrombocytopenias, marrow aspiration alone is sufficient, but for detection of disorders with focal marrow involvement bilateral marrow biopsies are a must.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Biópsia por Agulha
/
Medula Óssea
/
Doenças da Medula Óssea
/
Humanos
Tipo de estudo:
Estudo prognóstico
Idioma:
Inglês
Ano de publicação:
2002
Tipo de documento:
Artigo
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