Visual evoked responses in ethambutol induced optic neuritis.
Artigo
em Inglês
| IMSEAR
| ID: sea-85192
ABSTRACT
Pattern evoked responses were recorded in 46 patients of tuberculosis on ethambutol and 16 healthy subjects. Deterioration in visual acuity was documented in two patients (4.3%). P100 latency was delayed in 16 cases (34.8%), while in 12 patients (26.1%) both latency and amplitude were affected. A cut off latency value of > or = 140 ms was associated with ophthalmological findings. The incidence of subclinical toxicity as detected by visual evoked response (VER) was higher in older subjects, patients on higher doses of ethambutol (> or = 20 mg/kg/day) and longer duration of treatment. Of two cases with objective ocular signs, one who reported for follow up after two months had recovered completely after stopping ethambutol. Recording of VER is an extremely useful objective test for subclinical optic nerve damage.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Tempo de Reação
/
Idoso
/
Feminino
/
Humanos
/
Masculino
/
Acuidade Visual
/
Neurite Óptica
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Adolescente
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Adulto
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Etambutol
Idioma:
Inglês
Ano de publicação:
1997
Tipo de documento:
Artigo
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