Lithium carbonate therapy for induction of euthyroid state in thyrotoxicosis. A preliminary study.
Artigo
em Inglês
| IMSEAR
| ID: sea-85411
ABSTRACT
Lithium carbonate was tried in 27 patients with Graves' disease to induce euthyroid state. Each patient received 1200 mg of lithium carbonate in three divided doses. The study protocol included monthly monitoring of serum lithium, total serum T3, T4 and T3/T4 ratio, and a repeat radioactive iodine uptake (RAIU) at the end of three months. Twenty three patients completed the study. Of these, only 9 (39.1%) achieved euthyroid state, with a significant reduction in serum T3 and T4 but not in T3/T4 ratio and RAIU, suggesting a major effect of lithium on thyroid hormone release. No significant correlation was observed between serum lithium and circulating T3 and T4.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Hormônios Tireóideos
/
Tireotoxicose
/
Feminino
/
Humanos
/
Masculino
/
Carbimazol
/
Doença de Graves
/
Carbonato de Lítio
/
Adulto
/
Lítio
Idioma:
Inglês
Ano de publicação:
1990
Tipo de documento:
Artigo
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