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Progressive systemic sclerosis in south India.
Artigo em Inglês | IMSEAR | ID: sea-85529
ABSTRACT
Seventy eight patients with progressive systemic sclerosis (PSS) were seen over a period of 14 years. They were analysed after clinical, haematological, biochemical, immunological and radiological investigations for comparison with other Indian and Western studies. Nine of the 78 were cases of childhood PSS. There was a female preponderance (3.91) and the peak age of occurrence was the 4th decade (32.1%). Arthralgia (53.8%) and skin thickening (70.5%) were the common presenting symptoms. Raynaud's phenomenon (28.2%) was less common. Involvement of the skin was present in all the patients and skin biopsy was positive in 96% of the cases. Joints were affected in 66.7%; internal organs were involved in 52.6%. Antinuclear antibody was positive in 56.8%. Abnormal echocardiography (37.6%) and barium studies (20.4%) were seen. Restrictive airway pattern by pulmonary function test was present in 55%. Death occurred in 5 patients, of whom 3 died of severe pulmonary hypertension.
Assuntos
Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Assunto principal: Escleroderma Sistêmico / Idoso / Feminino / Humanos / Masculino / Criança / Fatores Sexuais / Incidência / Adolescente / Fatores Etários Tipo de estudo: Estudo de incidência / Estudo prognóstico País/Região como assunto: Ásia Idioma: Inglês Ano de publicação: 1991 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Assunto principal: Escleroderma Sistêmico / Idoso / Feminino / Humanos / Masculino / Criança / Fatores Sexuais / Incidência / Adolescente / Fatores Etários Tipo de estudo: Estudo de incidência / Estudo prognóstico País/Região como assunto: Ásia Idioma: Inglês Ano de publicação: 1991 Tipo de documento: Artigo