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Hairy cell leukemia--results with alpha interferon therapy.
Artigo em Inglês | IMSEAR | ID: sea-86062
ABSTRACT
Hairy cell leukemia (HCL) is a rare lymphoproliferative disorder. Although now multiple treatment options are being available, the optimal treatment of this disease still remains debatable. Inspite of the advent of newer purine analogues, in India recombinant interferon is the only freely available first line treatment. We report our experience of long term remissions in HCL with interferon alpha 2a. Of a total of 35 cases of HCL we were able to treat 19 cases with interferon. Of 18 evaluable cases an overall response of 88.9% was achieved. With a median follow up of 31 months a disease free survival was 83%. Thus with a dose of 3 million units s.c. daily for 6 months at least, we feel that a reasonably good long term remission can be obtained. The cost of the treatment however, is still a deterrent.
Assuntos
Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Assunto principal: Indução de Remissão / Idoso / Feminino / Humanos / Masculino / Leucemia de Células Pilosas / Interferon-alfa / Sepse / Intervalo Livre de Doença / Adulto Idioma: Inglês Ano de publicação: 1999 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Assunto principal: Indução de Remissão / Idoso / Feminino / Humanos / Masculino / Leucemia de Células Pilosas / Interferon-alfa / Sepse / Intervalo Livre de Doença / Adulto Idioma: Inglês Ano de publicação: 1999 Tipo de documento: Artigo