Diagnostic and prognostic utility of rapid strip (OptiMal and Paracheck) versus conventional smear microscopy in adult patients of acute, uncomplicated P. falciparum malaria in Mumbai, India.
Artigo
em Inglês
| IMSEAR
| ID: sea-86916
ABSTRACT
OBJECTIVES:
The present study compared the diagnostic and prognostic utility of two rapid tests the (Paracheck and OptiMal) versus conventional smear microscopy.METHODS:
Using two independent microscopists we carried out the three tests in 31 adult cases of smear positive, acute, uncomplicated Plasmodium falciparum malaria. All three tests were done pretreatment, and on Days 8, 15 and 29.RESULTS:
Compared to microscopy, the Paracheck had a sensitivity of 100%, while the OptiMal had a sensitivity of 83.7%. The lower sensitivity of OptiMal resulted from misidentification by both microscopists of 6/31 cases as Plasmodium vivax. As a follow up tool, the OptiMal was better than Paracheck, due to the earlier disappearance of the parasite LDH. Also in the Paracheck, between microscopists, there was a significant difference in reading the tests, on Days 8 and 15.CONCLUSION:
Our study reiterates, the continued utility of conventional smear microscopy.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Plasmodium falciparum
/
Kit de Reagentes para Diagnóstico
/
Feminino
/
Humanos
/
Masculino
/
Testes Sorológicos
/
Proteínas
/
Proteínas de Protozoários
/
Programas de Rastreamento
/
Estudos Transversais
Tipo de estudo:
Estudo diagnóstico
/
Estudo observacional
/
Estudo de prevalência
/
Estudo prognóstico
/
Fatores de risco
/
Estudo de rastreamento
Idioma:
Inglês
Ano de publicação:
2003
Tipo de documento:
Artigo
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