Safety and efficacy of liposomal amphotericin B in patients with cryptococcal meningitis.
Artigo
em Inglês
| IMSEAR
| ID: sea-88354
ABSTRACT
Four patients with cryptococcal meningitis were successfully treated with liposomal amphotericin B prepared at our institute using Soya phosphatidylcholine and cholesterol. In one patient, response with 1 mg/kg/day treatment was poor. However, on increasing the dose to 2 mg/kg/day, a good response was observed with CSF becoming negative for Cryptococcus neoformans after seven days of this enhanced dose. L-AMP-LRC-1 was found to be well tolerated and a major advantage was observed in two renal transplant patients in whom it could be given safely.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Infusões Intravenosas
/
Feminino
/
Humanos
/
Portadores de Fármacos
/
Anfotericina B
/
Seguimentos
/
Resultado do Tratamento
/
Meningite Criptocócica
/
Ensaios Clínicos Fase II como Assunto
/
Adulto
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Idioma:
Inglês
Ano de publicação:
2001
Tipo de documento:
Artigo
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