Postpartum posterior leukoencephalopathy syndrome.

ABSTRACT

In this report we are presenting three patients of posterior leukoencephalopathy syndrome developing in postpartum period. Two of these patients had persistent imaging abnormalities in posterior parietal and occipital regions leading to focal atrophy of brain along with permanent cortical blindness and recurrent seizures. In both the patients the syndrome was either unrecognized, or remained untreated on initial presentation. In third patient also the syndrome was not recognized for 10 days, initial clinical manifestations and computed tomographic (CT) abnormalities remained unchanged even after two months. Failure to early recognition and treatment can produce permanent brain damage and syndrome of posterior leukoencephalopathy may become irreversible.