Lipid peroxide levels in chronic renal failure.
Artigo
em Inglês
| IMSEAR
| ID: sea-88778
ABSTRACT
To determine presence of oxidant stress in chronic renal failure and to evaluate the efficacy of vitamin E in its amelioration, we studied 34 patients (Group I, age 32.4 +/- 11 years, MF 31) and 10 healthy controls (Group II, age 27.4 +/- 5 years, MF 41). The difference in baseline values of lipid peroxide (nmol/ml) was statistically significant (Group I 4.19 +/- 1.69, Group II 1.87 +/- 1.39, p = 0.004). Values of vitamin E (mg/l) were also significantly lower in Group I as compared to Group II (12.18 +/- 4.27 vs. 19.32 +/- 2.03, p = 0.003). Serum lipid peroxide values decreased significantly after supplementation with 400 mg/day of vitamin E for six weeks in Group I (4.19 +/- 1.69 to 3.21 +/- 1.13, p = 0.053) but not in Group II (1.87 +/- 1.39 to 1.03 +/- 0.87). Levels of vitamin E increased in both the groups (Group I 12.18 +/- 4.27 to 16.01 +/- 5.13, Group II 19.32 +/- 2.03 to 23.21 +/- 1.94, p < 0.005). No significant difference was observed in values of serum creatinine and urea before and after intervention.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Valores de Referência
/
Vitamina E
/
Feminino
/
Humanos
/
Masculino
/
Seguimentos
/
Adulto
/
Suplementos Nutricionais
/
Falência Renal Crônica
/
Testes de Função Renal
Tipo de estudo:
Ensaio Clínico Controlado
/
Estudo observacional
/
Estudo prognóstico
Idioma:
Inglês
Ano de publicação:
1999
Tipo de documento:
Artigo
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