Clinical profile in gelatinous bone marrow transformation.
Artigo
em Inglês
| IMSEAR
| ID: sea-89510
ABSTRACT
OBJECTIVE:
To study the clinical spectrum associated with gelatinous bone marrow transformation (GMT).METHODS:
All subjects whose bone marrow aspiration showed pink purple material on Leishman stain underwent a detail history, clinical examination and investigation (biochemical/microbiological/radiological). Additionally, in each subject the smear was stained with special stains of Periodic Acid Schiff and Alcian blue.RESULTS:
Out of total 1498 marrows, 65 showed evidence of GMT. All of these had anaemia. The associated clinical spectra of diseases noticed were Infection (31 cases), Nutritional deficiency (5 cases), Haematological disorders (Aplastic/toxic depression) (17 cases), Malignancies (3 cases), and Miscellaneous (9 cases).CONCLUSION:
Based on the heterogenecity of associated clinical disorders, GMT indicates severe illness and not a particular disease. GMT may be a result of bioregulatory process (which presently needs further prospective studies) that are activated in different pathologic conditions but resulting in similar lesion in the bone marrow and so till then it may be concluded that GMT is a symptom of bone marrow.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Biópsia por Agulha
/
Medula Óssea
/
Doenças da Medula Óssea
/
Idoso
/
Feminino
/
Humanos
/
Masculino
/
Criança
/
Pré-Escolar
/
Adolescente
Tipo de estudo:
Estudo observacional
Idioma:
Inglês
Ano de publicação:
2003
Tipo de documento:
Artigo
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