Nifedipine induced modulations of intra-thyroidal radio-iodine turnover kinetics in euthyroid and thyrotoxic patients.
Artigo
em Inglês
| IMSEAR
| ID: sea-89939
ABSTRACT
Nifedipine induced modulations of intrathyroidal radioiodine turnover kinetics has been studied in euthyroid and thyrotoxicosis individuals. Nifedipine has been found to suppress Amax significantly (p < 0.001), while transit kinetics k1 and k2 are not significantly affected. On the contrary, in the patients with thyrotoxicosis post-nifedipine Amax was not significantly different from pre-nifedipine study, while k1 was slightly suppressed (p < 0.05) and k2 was significantly elevated (p < 0.01). Apparently different Ca+2 dependent control mechanisms are operative in euthyroid and thyrotoxic states. Clinical implications of these observations have been discussed.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Glândula Tireoide
/
Tireotoxicose
/
Feminino
/
Humanos
/
Masculino
/
Nifedipino
/
Adulto
/
Radioisótopos do Iodo
/
Pessoa de Meia-Idade
Idioma:
Inglês
Ano de publicação:
1993
Tipo de documento:
Artigo
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