Short term anti-tubercular drug therapy and hepatic microsomal enzyme activity. Antipyrine metabolism as an index.
Artigo
em Inglês
| IMSEAR
| ID: sea-91112
ABSTRACT
The effect of short course chemotherapy on the drug metabolising capacity of the liver was studied in 7 newly diagnosed pulmonary tuberculosis patients, using antipyrine as a model drug. Antipyrine elimination half-life and plasma clearance rate were not significantly altered by 3 weeks of therapy. It is concluded that short course chemotherapy does not affect antipyrine metabolising enzyme activity.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Saliva
/
Fatores de Tempo
/
Tuberculose Pulmonar
/
Humanos
/
Masculino
/
Microssomos Hepáticos
/
Antipirina
/
Adulto
/
Avaliação de Medicamentos
/
Antituberculosos
Tipo de estudo:
Estudo prognóstico
Idioma:
Inglês
Ano de publicação:
1990
Tipo de documento:
Artigo
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