Effects of tamoxifen therapy on plasma lipid profile in patients of breast cancer.
Artigo
em Inglês
| IMSEAR
| ID: sea-91182
ABSTRACT
AIM:
To evaluate the effects of tamoxifen therapy on plasma lipid profile in patients of breast cancer.METHOD:
A total of 55 postoperative patients of breast cancer were given tablet tamoxifen 20mg orally daily for 6 months. Estimation of plasma lipid by standard method was carried out in both pre-menopausal and postmenopausal new patients of early stage breast cancer at 0 day, 3rd month and 6th months of therapy.RESULTS:
Suggested that in pre-menopausal and postmenopausal patient's TC and LDL-c levels were reduced significantly, whereas, TG, VLDL-c and HDL-c were not altered. Comparison of the effects of tamoxifen in pre-menopausal and postmenopausal patients on lipid profile revealed that fall in TC and LDL-c was significantly higher at both 3 and 6 months in postmenopausal patients.CONCLUSION:
The study demonstrates that tamoxifen to favorably alter the markers of cardiovascular risk in both pre-menopausal and postmenopausal patients of breast cancer.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Tamoxifeno
/
Triglicerídeos
/
Neoplasias da Mama
/
Idoso
/
Feminino
/
Humanos
/
VLDL-Colesterol
/
Adulto
/
Moduladores Seletivos de Receptor Estrogênico
/
HDL-Colesterol
Idioma:
Inglês
Ano de publicação:
2006
Tipo de documento:
Artigo
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