Acute superior mesenteric vein thrombosis associated with factor V 'Leiden' gene mutation.
Artigo
em Inglês
| IMSEAR
| ID: sea-91364
ABSTRACT
OBJECTIVES:
To study thrombophilia states in Indian patients with acute spontaneous superior mesenteric vein thrombosis (SMVT).METHODS:
Two men with this condition, a 56 year old and a 31 year old presenting with acute SMVT, demonstrated on CT scan, were subjected to a thrombophilia screen consisting of Protein C, S, antithrombin levels, lupus anticoagulant, anticardiolipin antibodies, fibrinogen levels, factor VIII levels, factor V 'Leiden' gene mutation, and paroxysmal nocturnal hematuria screen.RESULTS:
A thrombophilia screen showed factor V 'Leiden' gene mutation (heterozygous) in both cases. Additionally, the first patient had high fibrinogen levels and the second high factor VIII levels. Both patients are currently on long-term anticoagulation.CONCLUSION:
Factor V 'Leiden' gene mutation in association with other thrombophilic factors may predispose to spontaneous superior mesenteric vein thrombosis.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Humanos
/
Masculino
/
Fator V
/
Doença Aguda
/
Adulto
/
Trombofilia
/
Trombose Venosa
/
Heterozigoto
/
Oclusão Vascular Mesentérica
/
Veias Mesentéricas
Idioma:
Inglês
Ano de publicação:
2003
Tipo de documento:
Artigo
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