2-CdA in the treatment of hairy cell leukaemia.
Artigo
em Inglês
| IMSEAR
| ID: sea-91940
ABSTRACT
INTRODUCTION:
Hairy cell leukaemia (HCL) is a rare lymphoproliferative disorder. Treatment options available are splenectomy, interferon, DCF and 2-CdA. 2-CdA is considered to have curative potential as proved by the other studies.METHODS:
We gave 2-CdA in a dose of 0.09/kg/day as a continuous infusion in sixteen patients of hairy cell leukaemia.RESULTS:
Three patients developed neutropenia post transfusion. At the end of three months all patients were in remission. Two patients relapsed at the median follow-up of 15 months.CONCLUSION:
2-CdA in HCL can achieve complete remission, prolonged survival and care as well.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Feminino
/
Humanos
/
Masculino
/
Leucemia de Células Pilosas
/
2-Cloroadenosina
/
Desoxiadenosinas
/
Taxa de Sobrevida
/
Resultado do Tratamento
/
Adulto
/
Pessoa de Meia-Idade
Idioma:
Inglês
Ano de publicação:
2001
Tipo de documento:
Artigo
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