Cefoperazone monotherapy for serious infections in hospitalized patients--an initial Indian experience.
Artigo
em Inglês
| IMSEAR
| ID: sea-92084
ABSTRACT
Cefoperazone sodium is a broad spectrum third generation Cephalosporin recently introduced in India. This was used as a monotherapy to treat severe infections in hospitalized patients. These infections were due to various gram positive and gram negative organisms. Of the 22 evaluable patients, 21 (95%) were clinically cured and 1 (5%) improved. 18 pathogens were isolated from 17 patients. Microbiologic eradication was 100%. Symptomatic improvement occurred within 48-72 hours of onset of therapy with complete relief by 4-5 days. Dual mode of excretion makes this drug safe in presence of renal insufficiency. Anti-microbial activity against a wide spectrum of organisms and twice daily dosage schedule qualify Cefoperazone as a single antibiotic of choice in severe infections in critically ill patients.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Idoso de 80 Anos ou mais
/
Idoso
/
Feminino
/
Humanos
/
Masculino
/
Cefoperazona
/
Cefalosporinas
/
Adolescente
/
Resultado do Tratamento
/
Infecções por Bactérias Gram-Positivas
Limite:
Aged80
País/Região como assunto:
Ásia
Idioma:
Inglês
Ano de publicação:
1995
Tipo de documento:
Artigo
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