Sickle haemoglobin, G-6PD deficiency and malaria in western Orissa.
Artigo
em Inglês
| IMSEAR
| ID: sea-92805
ABSTRACT
Sixty cases of malaria were screened for sickle haemoglobin and G-6PD deficiency. Plasmodium vivax was detected in 40 (66%) and Plasmodium falciparum in 21 (35%) cases, with six of the latter having cerebral manifestation. Sickle Hb was found in 7 (11.5%) patients and G-6PD deficiency in 3 (5%) cases. Both patients with SS disease had vivax malaria, while of 5 with sickle cell trait 3 had only vivax, one only falciparum and one mixed infection. Amongst G-6PD deficient patients one had vivax and two falciparum malaria. One of the latter had both SC trait and G-6PD deficiency. Thus, adult persons with SS disease or SC trait were not found to be resistant to either vivax or falciparum malaria. A high frequency (5%) of G-6PD deficiency amongst malaria patients warrants a caution against indiscriminate use of 8-aminoquinoline drugs.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Plasmodium falciparum
/
Plasmodium vivax
/
Traço Falciforme
/
Humanos
/
Doença de Depósito de Glicogênio Tipo I
/
Criança
/
Adolescente
/
Adulto
/
Índia
/
Lactente
País/Região como assunto:
Ásia
Idioma:
Inglês
Ano de publicação:
1990
Tipo de documento:
Artigo
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