Silent myocardial ischemia and cardiac autonomic neuropathy in diabetics.
Artigo
em Inglês
| IMSEAR
| ID: sea-93074
ABSTRACT
OBJECTIVE:
To evaluate the association of silent myocardial ischemia (SMI) with cardiac autonomic neuropathy in asymptomatic diabetic patients. MATERIAL ANDMETHODS:
Two hundred asymptomatic patients of diabetes mellitus were assessed for evidence of cardiac autonomic neuropathy. Of these, 30 (15 males, 15 females; mean age 44.7 +/- 8.8 years) were found to have cardiac autonomic neuropathy. Thirty (30) age and sex matched diabetic patients (mean age 42.4 +/- 7.6 years) who had no evidence autonomic neuropathy were included in the study as control group. Both the groups of patients were evaluated for SMI by 24 hour ambulatory electrocardiographic (ECG) monitoring.RESULTS:
Incidence of SMI was significantly higher in patients with autonomic neuropathy 12/30 (40%) compared to those without 3/30 (10%) p < 0.001. Duration of diabetes was more (13 +/- 1.59 years) in patients with autonomic neuropathy compared to the control group (8.66 +/- 1.55 years) p < 0.001. Serum cholesterol and triglyceride levels were significantly higher in patients with autonomic neuropathy in comparison to control group < 0.05 and < 0.01, respectively. There was no difference in the pattern of SMI in the two groups (p = N.S).CONCLUSION:
Cardiac autonomic neuropathy predisposes patients with diabetes mellitus to SMI. Twenty four hour ambulatory ECG monitoring provides useful diagnostic information in early detection and evaluation of SMI in asymptomatic diabetic patients.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Sistema Nervoso Autônomo
/
Doenças do Sistema Nervoso Autônomo
/
Feminino
/
Humanos
/
Masculino
/
Fatores de Risco
/
Eletrocardiografia Ambulatorial
/
Isquemia Miocárdica
/
Adulto
/
Neuropatias Diabéticas
Tipo de estudo:
Estudo de etiologia
/
Fatores de risco
/
Estudo de rastreamento
Idioma:
Inglês
Ano de publicação:
1999
Tipo de documento:
Artigo
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