A preliminary study of antiphospholipid antibodies in 50 cases of bad obstetric history.
Artigo
em Inglês
| IMSEAR
| ID: sea-93080
ABSTRACT
The prevalence of the antiphospholipid antibodies in certain high risk groups like bad obstetric history is higher than previously realized. A pilot study in 50 patients of bad obstetric history, for the presence of lupus anticoagulant and anticardiolipin antibodies was carried out to establish an association between the presence of the antiphospholipid antibodies and recurrent fetal wastage. Lupus anticoagulant alone was positive in six patients (12%) and anticardiolipin antibody alone was positive in 14 patients (28%), while both lupus anticoagulant and anticardiolipin antibodies were positive in three patients (6%). Activated partial thromboplastin time (aPTT) and prothrombin time (PT) were not significantly prolonged. Platelet count was normal in all the patients. We conclude that lupus anticoagulant as based on kaolin clotting time and anticardiolipin antibodies are important tests to detect the etiology of fetal wastage.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Feminino
/
Humanos
/
Gravidez
/
Estudos de Casos e Controles
/
Projetos Piloto
/
Aborto Habitual
/
Inibidor de Coagulação do Lúpus
/
Anticorpos Antifosfolipídeos
/
Anticorpos Anticardiolipina
/
Gravidez de Alto Risco
Tipo de estudo:
Estudo observacional
/
Fatores de risco
Idioma:
Inglês
Ano de publicação:
1999
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS