Anti-neutrophil cytoplasmic antibody (ANCA) in necrotising vasculitides with renal involvement.
Artigo
em Inglês
| IMSEAR
| ID: sea-93112
ABSTRACT
Anti-neutrophil cytoplasmic antibody (ANCA) was detected in sera of 20 out of 32 patients with necrotising vasculitides involving the kidneys and other organs. It was of high titre and cytoplasmic type in Wegener's granulomatosis (8/9); and of low titre and cytoplasmic or perinuclear type in systemic polyarteritis (6/12), renal limited polyarteritis (5/9) and pulmonary renal syndrome (1/2). It fell to low or undetectable levels on clinical improvement or remission with cyclophosphamide therapy. Its detection was helpful in diagnosis and management of vasculitides with renal and extrarenal manifestations.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Poliarterite Nodosa
/
Autoanticorpos
/
Vasculite
/
Idoso
/
Feminino
/
Humanos
/
Masculino
/
Criança
/
Granulomatose com Poliangiite
/
Adolescente
Idioma:
Inglês
Ano de publicação:
1993
Tipo de documento:
Artigo
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