Oncogene.
Artigo
em Inglês
| IMSEAR
| ID: sea-94608
ABSTRACT
Recent studies have shown that activation of oncogenes, genes concerned with cell growth, and inactivation of anti-oncogenes may be responsible for uncontrolled cell proliferation leading to malignancy. These oncogenes code for products or proteins which are closely similar to growth factors or receptors of growth factors. Alterations in lipid metabolism in the form of excess formation of inositol triphosphate and relocation of protein kinase C, the second messengers of the mitotic process, can initiate cell division. Oncogenes can be activated by chromosomal aberrations induced by chemicals, viruses and drugs. The identification of oncogenes and their products may have relevance to the development of new therapeutic strategies in cancer.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Oncogenes
/
Humanos
/
Regulação Neoplásica da Expressão Gênica
/
Diferenciação Celular
/
Divisão Celular
/
Transformação Celular Neoplásica
/
Interferons
/
Ácidos Graxos
/
Lipídeos de Membrana
Tipo de estudo:
Estudo prognóstico
Idioma:
Inglês
Ano de publicação:
1992
Tipo de documento:
Artigo
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